Release 56
(Apr 24, 2025)

QTL 15898 Description:

 Trait Information
Trait name: Hematocrit Vertebrate Trait Ontology: n/a
Reported name: Packed red blood cell volume Product Trait Ontology: n/a
Symbol: HCT Clinical Measurement Ontology: Hematocrit
 QTL Map Information
Chromosome:23
QTL Peak Location:22.8 (cM)
QTL Span:22.87-23.07 (cM)
15.0-15.1 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:Association
Model tested:Mendelian
Test base:n/a
Threshold significance level:Significant
P_values0.0001
Dominance effect:n/a
Additive effect:n/a
Associated Gene:HSP90AB1 (heat shock protein 90kDa alpha (cytosolic), class B member 1)
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Bos taurus (crossbred Holstein Friesian) and Bos indicus (Thai native cattle, White Lamphun, and Mountain cattle) in Thailand.
     Breeds associated:
    n/a
    Design:Animals were genotyped for nine polymorphisms in HSP90AB1 and analyzed for heat tolerance traits.
    Analysis:Association analyses via regression on individual SNP genotypes, a repeated gene substitution MIXED model, and least square means were performed.
    Software:SAS
    Notes: 
    Links:Edit

     Reference
    Authors:Charoensook R, Gatphayak K, Sharifi AR, Chaisongkram C, Brenig B, Knorr C
    Affiliation:Institute of Veterinary Medicine, Georg-August-University Göttingen, 37077, Göttingen, Germany.
    Title:Polymorphisms in the bovine HSP90AB1 gene are associated with heat tolerance in Thai indigenous cattle
    Journal:Trop Anim Health Prod, 2012, 44(4): 921-8
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:SNP03
    User inputs on reference #22008953
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  • Cite this Data:

    Animal QTLdb: QTL15898 was published in 2012, and was curated into QTLdb on 2012-02-20. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:15898

     

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