Release 56
(Apr 24, 2025)

QTL 167744 Description:

 Trait Information
Trait name: Bovine tuberculosis susceptibility Vertebrate Trait Ontology: n/a
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: BTBS Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:6
QTL Peak Location:108.15 (cM)
QTL Span:108.15-108.15 (cM)
97.9-97.9 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs384707118
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Genome-wise
Threshold significance level:Significant
P_values<0.05
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Irish cattle of various pure and crossbreeds. The majority of the sires were purebred Charolais, Limousin, Holstein-Friesian, Aberdeen Angus, and Simmental.
     Breeds associated:
    Design:Sires were genotyped using a BovineHD, BovineSNP50, or custom-built genotyping panel. Data were imputed to HD, then to WGS, and SNP association with bovine tuberculosis infection was analyzed.
    Analysis:Mixed models were used for within-breed and across-breed single-SNP regression analysis.
    Software:WOMBAT, FImpute2, SAMtools, Beagle, Eagle, minimac3
    Notes: 
    Links:Edit

     Reference
    Authors:Ring S C, Purfield D C, Good M, Breslin P, Ryan E, Blom A, Evans R D, Doherty M L, Bradley D G, Berry D P
    Affiliation:Teagasc, Animal and Grassland Research and Innovation Centre, Moorepark, Fermoy, Co. Cork, Ireland
    Title:Variance components for bovine tuberculosis infection and multi-breed genome-wide association analysis using imputed whole genome sequence data
    Journal:PloS one, 2019, 14(2): e0212067
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #30763354
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  • Cite this Data:

    Animal QTLdb: QTL167744 was published in 2019, and was curated into QTLdb on 2019-02-20. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:167744

     

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