QTL Map Information |
Chromosome: | 16 |
QTL Peak Location: | 98.65 (cM) |
QTL Span: | 98.65-98.65 (cM) 77.7-77.7 (Mbp) |
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Upper, "Suggestive": | n/a |
Upper, "Significant": | n/a |
Peak: | rs109786180 |
Lower, "Significant": | n/a |
Lower, "Suggestive": | n/a |
Marker type: | SNP |
Analysis type: | Association |
Model tested: | Mendelian |
Test base: | Genome-wise |
Threshold significance level: | Significant |
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P_values | <0.05 | Dominance effect: | n/a |
Additive effect: | n/a |
Associated Gene: | n/a |
Cis/Trans acting type: |  |
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Extended information: |
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QTL Experiment in Brief |
Animals: | Animals were Irish cattle of various pure and crossbreeds. The majority of the sires were purebred Charolais, Limousin, Holstein-Friesian, Aberdeen Angus, and Simmental. |
Breeds associated:
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Design: | Sires were genotyped using a BovineHD, BovineSNP50, or custom-built genotyping panel. Data were imputed to HD, then to WGS, and SNP association with bovine tuberculosis infection was analyzed. |
Analysis: | Mixed models were used for within-breed and across-breed single-SNP regression analysis. |
Software: | WOMBAT, FImpute2, SAMtools, Beagle, Eagle, minimac3 |
Notes: | |
Links: | Edit |
Reference |
Authors: | Ring S C, Purfield D C, Good M, Breslin P, Ryan E, Blom A, Evans R D, Doherty M L, Bradley D G, Berry D P |
Affiliation: | Teagasc, Animal and Grassland Research and Innovation Centre, Moorepark, Fermoy, Co. Cork, Ireland |
Title: | Variance components for bovine tuberculosis infection and multi-breed genome-wide association analysis using imputed whole genome sequence data |
Journal: | PloS one, 2019, 14(2): e0212067 |
Links: |
PubMed | Abstract | List all data
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