Release 56
(Apr 24, 2025)

QTL 169919 Description:

 Trait Information
Trait name: M. paratuberculosis susceptibility Vertebrate Trait Ontology: n/a
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: MPARA Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:18
QTL Peak Location:67.57 (cM)
QTL Span:67.57-67.57 (cM)
51.6-51.6 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs452019112
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Genome-wise
Threshold significance level:Significant
P_values<0.05
Dominance effect:n/a
Additive effect:n/a
Associated Gene:TEX101 (testis expressed 101)
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Irish dairy cattle with >87.5% Holstein-Friesian background.
     Breeds associated:
    Design:Animals were initially genotyped using one of seven Illumina arrays, with data imputed to HD, and analyzed for humoral immune response to Mycobacterium avium subspecies paratuberculosis.
    Analysis:Linear mixed models were used.
    Software:ASReml, FImpute2, SAMtools, Beagle, WOMBAT
    Notes: 
    Links:Edit

     Reference
    Authors:McGovern S P, Purfield D C, Ring S C, Carthy T R, Graham D A, Berry D P
    Affiliation:Teagasc, Animal & Grassland Research and Innovation Centre, Moorepark, Fermoy, Co. Cork, Ireland P61C996
    Title:Candidate genes associated with the heritable humoral response to Mycobacterium avium subspecies paratuberculosis in dairy cows have factors in common with gastrointestinal diseases in humans
    Journal:Journal of dairy science, 2019, 102(5):4249-4263
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #30852025
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  • Cite this Data:

    Animal QTLdb: QTL169919 was published in 2019, and was curated into QTLdb on 2019-04-04. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:169919

     

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