| QTL Map Information |
|---|
| Chromosome: | 11 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
|
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Upper, "Suggestive": | n/a |
| Upper, "Significant": | rs135661502 |
| Peak: | |
| Lower, "Significant": | rs42635701 |
| Lower, "Suggestive": | n/a |
| Marker type: | Haplotype |
| Analysis type: | QTL |
| Model tested: | n/a |
| Test base: | Comparison-wise |
| Threshold significance level: | Significant |
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P_values | 5.435E-13 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | n/a |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Holstein cattle. |
| Breeds associated:
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| Design: | Animals were genotyped using several routinely available array chips, with data imputed to high density, and GWAS was performed for multiple births. A total of 691,222 SNPs were used for analysis. The most significantly associated regions were tested for association with other fertility traits. |
| Analysis: | Single-SNP regression was carried out using a mixed-model approach. Window-based association analyses were performed using a BayesB method. Haplotype analysis was also conducted. |
| Software: | GCTA, GenSel, PLINK, snp1101, VCTtools v0.1.16 |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Widmer S, Seefried FR, von Rohr P, Häfliger IM, Spengeler M, Drögemüller C |
| Affiliation: | Institute of Genetics, Vetsuisse Faculty, University of Bern, 3012, Bern, Switzerland |
| Title: | A major QTL at the LHCGR/FSHR locus for multiple birth in Holstein cattle |
| Journal: | Genetics, Selection, Evolution : GSE, 2021, 53(1): 57 |
| Links: |
PubMed | Abstract | List all data
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