Release 56
(Apr 24, 2025)

QTL 37506 Description:

 Trait Information
Trait name: Antibody titer to KLH antigen Vertebrate Trait Ontology: Blood immunoglobulin amount
Reported name: Antibody titer to KLH antigen Product Trait Ontology: n/a
Symbol: ABKLH Clinical Measurement Ontology: Antibody titer
 QTL Map Information
Chromosome:5
QTL Peak Location:0.00 (cM)
QTL Span:n/a
10.5-10.5 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs15660844
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:n/a
Threshold significance level:Significant
P_values0.0251
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Birds were from nine commercial purebred layer lines: four Rhode Island Red lines and five White Leghorn lines.
     Breeds associated:
    Design:Birds were genotyped for 1022 SNPs and analyzed for association with immunological traits.
    Analysis:First, each SNP was fitted individually as a fixed effect in a general linear model. Then, potentially interesting SNPs were verified in a mixed model.
    Software:ASReml, R software
    Notes: 
    Links:Edit

     Reference
    Authors:Sun Y, Biscarini F, Bovenhuis H, Parmentier H K, van der Poel J J
    Affiliation:Animal Breeding and Genomics Centre, Wageningen University, PO Box 338, 6700 AH Wageningen, the Netherlands
    Title:Genetic parameters and across-line SNP associations differ for natural antibody isotypes IgM and IgG in laying hens
    Journal:Animal genetics, 2013, 44(4): 413-24
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:IgM; 20 weeks
    User inputs on reference #23777392
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  • Cite this Data:

    Animal QTLdb: QTL37506 was published in 2013, and was curated into QTLdb on 2015-04-01. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:37506

     

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