Whole genome analysis for QTL/association enrichment
Running...
Version: Enrich S: beta v0.8
Data:
Number of blood parameters traits:
20
Number of QTL / associations found:
296
Number of chromosomes where QTL / associations are found:
27
Chi-squared (χ2) test: are blood parameters traits over-represented on some chromosomes?
Chromosomes
Total χ2
df
p-values
FDR *
Size of χ2
Chromosome X
181.08360
26
3.475172e-25
2.345741e-24
Chromosome 1
807.36740
26
1.939216e-153
5.235883e-152
Chromosome 2
529.52960
26
2.680138e-95
2.412124e-94
Chromosome 3
529.52960
26
2.680138e-95
2.412124e-94
Chromosome 4
66.48900
26
2.122276e-05
4.092961e-05
Chromosome 5
117.84040
26
1.176997e-13
4.539846e-13
Chromosome 6
44.93500
26
0.01196581
1.900452e-02
Chromosome 7
1.69160
26
0.998329325823115
9.999208e-01
Chromosome 8
90.34040
26
4.902864e-09
1.103144e-08
Chromosome 9
1.96200
26
0.998329325823115
9.999208e-01
Chromosome 10
16.01600
26
0.935817
9.999208e-01
Chromosome 11
1.96200
26
0.998329325823115
9.999208e-01
Chromosome 12
64.86740
26
3.594853e-05
6.066314e-05
Chromosome 13
16.01600
26
0.935817
9.999208e-01
Chromosome 14
115.67820
26
2.790976e-13
7.535635e-13
Chromosome 15
16.82680
26
0.9142221
9.999208e-01
Chromosome 16
64.86740
26
3.594853e-05
6.066314e-05
Chromosome 17
0.00260
26
0.998329325823115
9.999208e-01
Chromosome 18
7.02960
26
0.9999208
9.999208e-01
Chromosome 19
146.55660
26
8.940053e-19
4.023024e-18
Chromosome 20
0.00260
26
0.998329325823115
9.999208e-01
Chromosome 21
90.34040
26
4.902864e-09
1.103144e-08
Chromosome 22
88.44840
26
9.865396e-09
2.048967e-08
Chromosome 23
115.67820
26
2.790976e-13
7.535635e-13
Chromosome 24
115.67820
26
2.790976e-13
7.535635e-13
Chromosome 25
146.55660
26
8.940053e-19
4.023024e-18
Chromosome 26
28.65120
26
0.3271803
4.907704e-01
Chi-squared (χ2) test: Which of the 20 blood parameters traits are over-represented in the QTLdb
Traits
Total χ2
df
p-values
FDR *
Size of χ2
Blood albumin level
14.6865
19
0.7423037
8.732985e-01
Blood alpha-1 globulin level
9.57144
19
0.9627377
9.839736e-01
Blood beta-globulin level
21.50586
19
0.3095340
5.627891e-01
Blood gamma-globulin level
15.44446
19
0.6939611
8.674514e-01
Blood globulin level
15.44446
19
0.6939611
8.674514e-01
Blood total protein level
36.98425
19
0.007971039
2.277440e-02
Change in hematocrit
41.29761
19
0.002202538
1.122463e-02
Cholesterol level (total)
8.25001
19
0.9839736
9.839736e-01
Cortisol level
147.00001
19
8.293024e-22
1.658605e-20
Hematocrit
37.99816
19
0.005937909
1.979303e-02
Hemoglobin
18.87806
19
0.4646835
6.666946e-01
Mean corpuscular hemoglobin concentration
41.23567
19
0.002244925
1.122463e-02
Mean corpuscular hemoglobin content
18.84706
19
0.4666862
6.666946e-01
Mean corpuscular volume
27.49839
19
0.09356904
1.871381e-01
Pepsinogen level
38.58552
19
0.004995177
1.979303e-02
Platelet count
44.96439
19
0.0006933082
6.933082e-03
Red blood cell count
20.24378
19
0.3800452
6.334087e-01
Red blood cell distribution width
28.54951
19
0.07340922
1.631316e-01
Sodium level
28.60001
19
0.07254262
1.631316e-01
creatinine level
9.57144
19
0.9627377
9.839736e-01
Correlations found between some of these traits for your reference
No correlation data found on these traits
Overall Test
Data
Chi'Square Test
Fisher's Exact Test
Number of chrom.:
27
χ2
=
3405.946800
Number of traits:
20
df
=
494
Number of QTLs:
296
p-value
=
0
FOOT NOTE: * : FDR is short for "false
discovery rate", representing the expected proportion of type I errors. A type I
error is where you incorrectly reject the null hypothesis, i.e. you get a false
positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where
V = Number of Type I errors (false positives); R = Number of rejected hypotheses.
Benjamini–Hochberg procedure is a practical way to estimate FDR.
Running...
